UNDP operates in Uzbekistan since 1993 in accordance with the "Agreement between the Government of the Republic of Uzbekistan and the United Nations Development Programme" (signed on 10 June 1993 and amended on April 25, 2000.)

UNDP Resident Representative in Uzbekistan also coordinates the operations of all other UN agencies in Uzbekistan.

Currently, UN Resident Coordinator and UNDP Resident Representative in Tashkent is Stefan Priesner.

Since 1999 preparation and implementation of projects is based on the UNDP Country Programme Action Plan (CPAP), which first provided three year cycle of assistance to Uzbekistan (until 2005), then five year, and since 2010 – six year.

The main objective of the CPAP is provision of technical and advisory assistance to the Government of the Republic in addressing short-term and medium-term priority objectives related to socio-economic development of the country.

Main directions of the ongoing cooperation between Uzbekistan and UNDP identified by the UN Development Assistance Framework for the Republic of Uzbekistan for the period of 2010 - 2015, UNDP CPAP 2010 - 2015 and Action Plan for the implementation of the CPAP, signed by UNDP and the Government of the Republic of Uzbekistan.

On May 22-25, 2011 and on October 15-20, 2014 Deputy Secretary-General of the United Nations, UNDP Administrator H.Clark visited Uzbekistan.

Within she had meetings with the President of the Republic of Uzbekistan I.Karimov, the First Deputy Prime Minister, the Minister of Finance R.Azimov, Ministers of Foreign Affairs, Economy and External Economic Relations, Investments and Trade.

At the same time, H.Clark visited Tashkent, Bukhara and Khorezm regions.

Since 1993 until 2014, UNDP implemented in Republic of Uzbekistan 227 projects, for more than 191.6 million US dollars. In 2015, UNDP is implementing in Uzbekistan 29 projects for more than 15.7 million US dollars.

UNDP supports national partners in the implementation of projects in the following areas:

- Management of social-economic development and the fight against poverty (development of rural areas, private sector and micro-finance, capacity building of the development and provision of policy advice, also on fighting with HIV / AIDS, improving information and communication technologies);

- Environmental management and energy consumption (preservation of biodiversity, efficient land use, waste management and pollution control, energy efficiency);

- Management development of democratization processes (professional training of national cadres, strengthening social partnerships, development of civil society, human rights, development of democratic institutions).